Bilateral adrenal myolipomas
Uroradiology & genital male imaging
Case TypeClinical Cases
AuthorsP. Papanagiotou, A. H. Karantanas
Patient72 years, female
Abdominal ultrasonography disclosed a mass lesion, which was originally thought to be intrahepatic. Computed tomography (CT) showed well-delineated hypodense mass lesions on both adrenal glands. For further evaluation, MR imaging of the adrenals was performed. The MR imaging study was performed with a body phased array coil applying T2-weighted TSE, T2-weighted TSE with fat suppression and contrast enhanced T1-weighted Spin Echo with fat suppression. The examination revealed bilateral adrenal masses, 44mm in longitudinal diameter on the right side and 12mm on the left side. The lesions were heterogeneously hyperintense on T1- and T2-weighted images, with a marked decrease in the high signal following fat suprression. After administration of paramagnetic contrast, only the non-fatty components of the right lesion were enhanced. A second mass was detected, 15mm in diameter, originating from the outer limb of the left adrenal. The imaging findings suggested a diagnosis of bilateral adrenal myelolipomas associated with left adrenal adenoma.
Because the right-side tumour had been symptomatic, it was treated by right adrenalectomy. Histology confirmed the imaging findings.
To the best of our knowledge only 14 cases of bilateral adrenal myelolipomas have been reported in the literature.
US, CT and MR imaging during workup for unrelated symptoms identify most myelolipomas. CT images depict the location and size of the myelolipoma and may detect calcification, haemorrhage, fat and pseudocapsule. The typical image demonstrates a well-delineated mass, which has fatty tissue with areas of haematopoietic tissue exhibiting higher attenuation. On MR imaging, T1-weighted images show a high intensity mass with heterogeneity. The high intensity areas correspond to fat. On the T2-weighted images the fatty tissue and the bone marrow have a heterogeneously hyperintense appearance. Fat-suppressed images prove the existence of fat tissue in the lesion (5).
Differential diagnosis includes lipoma, liposarcoma (in cases with high lipid content), haemorrhagic adrenal adenoma, adrenocortical carcinoma, and adenocarcinoma metastatic to the adrenal gland (5). Radiologically-guided fine-needle aspiration is helpful in establishing the diagnosis. Acute haemorrhage is a complication of adrenal myelolipomas. Surgical excision of asymptomatic myelolipomas is not necessary.
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[5] 4. Rao P, Kenney PJ, Wagner BJ, Davidson AJ. Imaging and pathologic features of myelolipoma. Radiographics 1997 Nov-Dec;17(6):1373-85. (PMID: 9397452)
URL: | https://www.eurorad.org/case/1927 |
DOI: | 10.1594/EURORAD/CASE.1927 |
ISSN: | 1563-4086 |