CASE 16661 Published on 23.03.2020

Testicular teratoma in a 16-year-old teenager


Paediatric radiology

Case Type

Clinical Cases


Olga María Suárez Traba, Inés Solís Muñiz, Teresa María Cañas Maciá, María Isabel Rozas Gómez, Elena García Esparza, Gustavo Albi Rodríguez, Sara Inmaculada Sirvent Cerdá, Miguel Angel López Pino

Hospital Universitario Niño Jesús, Av. de Menéndez Pelayo, 65, 28009, Madrid, Spain


16 years, male

Area of Interest Genital / Reproductive system male, Oncology, Paediatric ; Imaging Technique Ultrasound
Clinical History

A 16-year-old patient who underwent right orchidopexy in 2017 due to cryptorchidism, was admitted at our Department of Radiology to perform a testicular ultrasound. A left testicular mass was observed. After carrying out an extension study, he was scheduled for an orchiectomy which was performed without complications.

Imaging Findings

- Testicular Ultrasound: The left testicle was slightly increased in size with respect to the contralateral one, with a large lesion occupying its middle and distal third. The lesion was very heterogeneous, with a multiseptated cystic appearance (Fig. 1) and some calcifications located in its upper margin (Fig. 2a, b). The lesion measured 31 x 32 mm (maximum axes) and no significant vascularisation in the colour Doppler study was observed (Fig. 3). The rest of the left testicular parenchyma had several hyperechogenic foci compatible with microlithiasis (Fig. 4).

- Left epididymis and scrotal covers did not present alterations.

- Isolated microlithiases were observed in the right testicle.

- Abdominal ultrasound and chest radiography did not identify any significant findings.

- Hormonal study was normal: alpha-fetoprotein 1.83 ng/ml (normal reference values 1-15) and B-HCG < 1.2 mIU/ml (normal reference values 0.01-5).


Testicular tumours represent 1-2% of solid neoplasms in childhood and are usually diagnosed at two peaks of age: at 2-4 years and towards 15 years. The approximate incidence in the general population is 0.5-2/100,000 [1, 2, 3, 4, 16].

Several risk factors have been described in the literature associated with the development of testicular tumours, the most frequent are: history of testicular maldescent, history of orchidopexy, testicular atrophy, previous germ cell tumour in the contralateral testicle, history of germ cell tumour in a 1st degree relative, infertility, Klinefelter syndrome, etc. [5, 6, 7]

Another risk factor related to the development of testicular tumours and widely discussed in the literature is the presence of microlithiasis [7, 8, 9, 10]. There are articles that show a very direct relationship in both adults and children [9, 10], while others refute this theory [8, 7].

In this case, our patient presented with bilateral isolated testicular microlithiasis and although he had a history of cryptorchidism, it was on the contralateral side.

Testicular tumours are divided into 6 groups according to the Pathological Classification of the World Health Organization 2016 [11]. In this classification, two types of teratomas are differentiated, prepubertal type and postpubertal type, with better prognosis for the first one [11, 12].

Teratomas are usually benign in prepubertal patients, but they can be malignant when they appear in adults [17]. Histologically, they present a combination of the 3 primitive embryological layers (ectoderm, endoderm and mesoderm) and its appearance is frequently heterogeneous. In ultrasound they present a variable appearance: simple cysts, multicystic lesions or solid-cystic lesions. Both diffuse and localised calcifications are frequent and their size can be variable, from small to voluminous lesions [4, 13, 14,16]. In the case we present, the teratoma was multiseptated with some localised calcifications in its upper pole.

Orchiectomy is the treatment of choice, although in recent years several articles have published a conservative surgical approach with tumorectomy in those patients included in the benign testicular tumour criteria (like small size, viable normal testicular tissue in US and negative tumour markers) [3, 15].

Written informed patient consent for publication has been obtained.

Differential Diagnosis List
Teratoma, postpubertal type
Subacute testicular haematoma
Hydatid cyst
Granulosa cell tumour
Testicular cystic displasia
Final Diagnosis
Teratoma, postpubertal type
Case information
ISSN: 1563-4086