Abrikossoff´s tumour, better known as granular cell tumour, was at first described as a granular cell myoblastoma because it was thought to arise from muscle cells, but now it is known that it originates from Schwann cells of peripheral nerves. [1, 4].
It is a rare neoplasm more frequently found in oral cavity and soft tissues, and in only 5-8% in the breast, most often in premenopausal black women, and uncommon but described in children and men [2, 4].
Usually it is benign but it must be treated with wide local excision to prevent recurrences, although they are rare. There are cases documented as malignant, even with metastases, which are treated with adjuvant therapy in addition to wide local excision [2, 3].
Clinically it manifests as a palpable, firm and painless mass that can be fixed to the pectoral fascia and associated with skin retraction, simulating a malignant lesion [1-3].
A variety of radiological manifestations have been described, lesions usually measure 3 cm or less, can show the appearance of a benign tumour and more frequently of a malignant tumour because of the infiltrative growth pattern of this tumour. On mammography and US findings range from round, well circumscribed tumour, with posterior enhancement by US, to spiculated, irregular and ill-defined mass, with no calcification, posterior shadow and hyperechogenic halo, due to an infiltrative growth pattern [1, 2, 4]. At MRI this tumour has been described on T1-weighted as a mass with homogeneous enhancement after gadolinium administration, or with rapid peripheral enhancement, seen also in sites other than the breast and suggestive of malignancy. And on T2-weighted as a hypointense mass, with a hyperintense rim. Finally, MRI should be performed if there is histological evidence of malignancy [2, 4].
As conclusion, Abrikossoff´s tumour is a rare neoplasm in the breast, and it is impossible to distinguish it clinically or radiographically, without biopsy, from other neoplasms of the breast and to define whether it is benign or malignant .