EURORAD ESR

Case 9544

T2* GRE MR imaging in Wilson disease

Author(s)
Arora A, Mukund A, Thapar S, Jain D

Department of Radiodiagnosis,
Institute of Liver and Biliary Sciences;
D-1 Vasant Kunj, 110070 New Delhi, India;
Email:aroradrankur@yahoo.com
 
Patient
male, 30 year(s)
 
 
  • Figure 1
    T2* GRE MR imaging

    Symmetrical T2-hypointensity of the caudate nuclei can be observed in this image.

     
    Area of Interest: Neuroradiology brain; Imaging Technique: MR; Procedure: Diagnostic procedure; Special Focus: Metabolic disorders;
     
     
  • Figure 2
    T2* GRE MR imaging

    Signal drop is seen in the bilateral caudate and lentiform nuclei. The ventricular system appears prominent for the age.

     
    Area of Interest: Neuroradiology brain; Imaging Technique: MR; Procedure: Diagnostic procedure; Special Focus: Metabolic disorders;
     
     
  • Figure 3
    T2* GRE MR imaging

    Marked signal loss can be seen in bilateral basal ganglia.

     
    Area of Interest: Neuroradiology brain; Imaging Technique: MR; Procedure: Diagnostic procedure; Special Focus: Metabolic disorders;
     
     
  • Figure 4
    T2* GRE MR imaging

    Symmetrical signal drop is seen involving the substantia nigra bilaterally.

     
    Area of Interest: Neuroradiology brain; Imaging Technique: MR; Procedure: Diagnostic procedure; Special Focus: Metabolic disorders;
     
     
  • Figure 5
    T2* GRE MR imaging

    Bilateral dentate nuclei also show signal drop on T2* GRE MR imaging.

     
    Area of Interest: Neuroradiology brain; Imaging Technique: MR; Procedure: Diagnostic procedure; Special Focus: Metabolic disorders;
     
     
  • Figure 6
    Corresponding T2-weighted FSE MRI
     

    No significant signal alteration can be seen in the caudate nuclei on this corresponding T2-weighted image.

     
    Area of Interest: Neuroradiology brain; Imaging Technique: MR; Procedure: Diagnostic procedure; Special Focus: Metabolic disorders;

    Subtle T2-hypointensity is seen involving the globus pallidi; it is disproportionately less pronounced as compared to the corresponding T2*GRE image.

     
    Area of Interest: Neuroradiology brain; Imaging Technique: MR; Procedure: Diagnostic procedure; Special Focus: Metabolic disorders;

    No significant signal alteration is seen in the substantia nigra.

     
    Area of Interest: Neuroradiology brain; Imaging Technique: MR; Procedure: Diagnostic procedure; Special Focus: Metabolic disorders;

    A very subtle hypointensity is seen in the region of dentate nuclei.

     
    Area of Interest: Neuroradiology brain; Imaging Technique: MR; Procedure: Diagnostic procedure; Special Focus: Metabolic disorders;
     
     
Symmetrical T2-hypointensity of the caudate nuclei can be observed in this image.
 
Signal drop is seen in the bilateral caudate and lentiform nuclei. The ventricular system appears prominent for the age.
 
Marked signal loss can be seen in bilateral basal ganglia.
 
Symmetrical signal drop is seen involving the substantia nigra bilaterally.
 
Bilateral dentate nuclei also show signal drop on T2* GRE MR imaging.
 
No significant signal alteration can be seen in the caudate nuclei on this corresponding T2-weighted image.
 
Subtle T2-hypointensity is seen involving the globus pallidi; it is disproportionately less pronounced as compared to the corresponding T2*GRE image.
 
No significant signal alteration is seen in the substantia nigra.
 
A very subtle hypointensity is seen in the region of dentate nuclei.
 
 
 
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