CASE 891 Published on 22.02.2001

Granulosa Cell Tumor of the Ovary

Section

Genital (female) imaging

Case Type

Clinical Cases

Authors

W. Volders, M. Billen, P. Claes, J. Gelin, Y. Palmers

Patient

87 years, female

Categories
No Area of Interest ; Imaging Technique Ultrasound, CT, MR
Clinical History
Abdominal distention since 2 months. Physical examination revealed a palpable abdominal mass. Small bowel peristalis was normal. Laboratory tests were normal.
Imaging Findings
The patient was admitted to the hospital with distention of the abdomen of about 2 months duration. There were no other complaints. Physical examination revealed a palpable abdominal mass. Small bowels peristalis was normal. On admission, laboratory tests were normal. Plain radiograph, ultrasonography and CT scan of the abdomen were performed.
Discussion
Granulosa cell tumor is a low-grade malignant neoplasm and accounts for only 2-3% of all ovarian tumors. Although uncommon, this tumor has also been described in the male testis. Based on clinical presentation and histological characteristics, distinction is made between a juvenile and adult type. Patients present with non-specific symptoms such as abdominal pain, distention or bloating and, in a majority of cases, with endocrine manifestations due to hormonal activity of the tumor. The CT appearance of granulosa cell tumors is that of a large, well-defined low-attenuation ovarian mass and is slightly different from that of epithelial ovarian carcinoma, which is more amorphous and less clearly defined. Granulosa cell tumors commonly contain solid and multicystic, posthemorrhagic components, which also are different from those of other ovarian cancers. CT scan is recommended for diagnosis and staging. Large size of the tumor, presence of enlarged lymph nodes and ascites are prognostically unfavorable signs. Nevertheless, surgical staging remains the gold standard, as extrapelvic lymph nodes may measure only a few millimeters and involvement mat be detected only by histology or cytology of peritoneal washings. As for other ovarian cancers, CT is furthermore recommended for identifying residual disease following surgery, during follow-up and for detection of recurrence.
Differential Diagnosis List
Granulosa Cell Tumor of the Ovary
Final Diagnosis
Granulosa Cell Tumor of the Ovary
Case information
URL: https://www.eurorad.org/case/891
DOI: 10.1594/EURORAD/CASE.891
ISSN: 1563-4086