EURORAD ESR

Case 15380

Primary dural lymphoma (PDL)

Author(s)
María Conde Martín, Laura Koren Fernandez, Aurelio Hernandez Lain, Carlos Fernandez Cabrera, Ana Ramos González

University Hospital 12 de Octubre,
Radiology;
Av. Cordoba
28041 Madrid;
Email:mariacondemar@hotmail.com
 
Patient
female, 55 year(s)
 
 
  • Figure 1
    Axial T2 and FLAIR
     

    The tumour shows iso-signal intensity on T2WI

     
    Area of Interest: Neuroradiology brain; Imaging Technique: MR; Procedure: Diagnostic procedure; Special Focus: Neoplasia;

    The tumour shows iso-signal intensity on FLAIR.

     
    Area of Interest: Neuroradiology brain; Imaging Technique: MR; Procedure: Diagnostic procedure; Special Focus: Neoplasia;
     
     
  • Figure 2
    Axial DWI and ADC
     

    Axial DWI high b-value. Difussion restriction is demonstrated.

     
    Area of Interest: Neuroradiology brain; Imaging Technique: MR-Diffusion/Perfusion; Procedure: Diagnostic procedure; Special Focus: Neoplasia;

    ADC map displays low ADC.

     
    Area of Interest: Neuroradiology brain; Imaging Technique: MR-Diffusion/Perfusion; Procedure: Diagnostic procedure; Special Focus: Neoplasia;
     
     
  • Figure 3
    Axial postgadolinium T1WI

    After paramagnetic contrast intravenous injection, the lesion demonstrates intense enhancement.

     
    Area of Interest: Neuroradiology brain; Imaging Technique: MR; Procedure: Diagnostic procedure; Special Focus: Neoplasia;
     
     
  • Figure 4
    CT scan

    CT scan with bone window shows right frontal bone sclerosis and involvement of both cranial tables with periosteal reaction. Note the absence of bone destruction.

     
    Area of Interest: Neuroradiology brain; Imaging Technique: CT; Procedure: Diagnostic procedure; Special Focus: Neoplasia;
     
     
  • Figure 5
    PET-CT scan of the whole body
     

    A PET-CT scan of the whole body demonstrates increased metabolic activity in a posterior mediastinal lymph node.

     
    Area of Interest: Lymph nodes; Imaging Technique: PET-CT; Procedure: Diagnostic procedure; Special Focus: Neoplasia;

    A PET-CT scan of the whole body reveals increased metabolic activity in the L5 vertebral body.

     
    Area of Interest: Musculoskeletal spine; Imaging Technique: PET-CT; Procedure: Diagnostic procedure; Special Focus: Neoplasia;
     
     
  • Figure 6
    PET-CT scan

    After chemotherapy treatment a PET-CT scan of the whole body shows that the increased metabolic activity had disappeared.

     
    Area of Interest: Musculoskeletal spine; Imaging Technique: PET-CT; Procedure: Diagnostic procedure; Special Focus: Neoplasia;
     
     
  • Figure 7
    Anatomical pathology
     

    Dura mater, bone and skeletal muscle infiltrated by neoplastic proliferation of high cell density, constituted by large cells, irregular nuclei and scarce cytoplasm (H&E, x4)

     
    Area of Interest: Forensic / Necropsy studies; Imaging Technique: Absorptiometry / Bone densiometry; Procedure: Diagnostic procedure; Special Focus: Lymphoma;

    Dura mater, bone and skeletal muscle infiltrated by neoplastic proliferation of high cell density, constituted by large cells, irregular nuclei and scarce cytoplasm (H&E, x10)

     
    Area of Interest: Forensic / Necropsy studies; Imaging Technique: Absorptiometry / Bone densiometry; Procedure: Diagnostic procedure; Special Focus: Lymphoma;
     
     
The tumour shows iso-signal intensity on T2WI
 
The tumour shows iso-signal intensity on FLAIR.
 
Axial DWI high b-value. Difussion restriction is demonstrated.
 
ADC map displays low ADC.
 
After paramagnetic contrast intravenous injection, the lesion demonstrates intense enhancement.
 
CT scan with bone window shows right frontal bone sclerosis and involvement of both cranial tables with periosteal reaction. Note the absence of bone destruction.
 
A PET-CT scan of the whole body demonstrates increased metabolic activity in a posterior mediastinal lymph node.
 
A PET-CT scan of the whole body reveals increased metabolic activity in the L5 vertebral body.
 
After chemotherapy treatment a PET-CT scan of the whole body shows that the increased metabolic activity had disappeared.
 
Dura mater, bone and skeletal muscle infiltrated by neoplastic proliferation of high cell density, constituted by large cells, irregular nuclei and scarce cytoplasm (H&E, x4)
 
Dura mater, bone and skeletal muscle infiltrated by neoplastic proliferation of high cell density, constituted by large cells, irregular nuclei and scarce cytoplasm (H&E, x10)
 
 
 
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