EURORAD ESR

Case 14811

Schwannoma in intraconal space of orbit is an underreported entity

Author(s)
Shamsh Tabrez Alam, Shazia; Saifullah Khalid, Prerna

JNMCH,
Amu; Street No.8
202002 Aligarh, India;
Email:khanhazik@gmail.com
 
Patient
female, 18 year(s)
 
 
  • Figure 1
    MR
     

    T1 –weighted sagittal image shows elongated hypointense lesion in orbit.

     
    Area of Interest: Neuroradiology peripheral nerve; Imaging Technique: MR; Procedure: Diagnostic procedure; Special Focus: Neoplasia;

    T2 w coronal image shows relatively well -circumscribed hyperintensity lesion in the superomedial quadrant of intraconal space of left orbit with inseparable fat plane with optic nerve.

     
    Area of Interest: Neuroradiology peripheral nerve; Imaging Technique: MR; Procedure: Diagnostic procedure; Special Focus: Neoplasia;

    Axial FLAIR image shows well-defined iso to hypointensity lesion in the intraconal space of left orbit.

     
    Area of Interest: Neuroradiology peripheral nerve; Imaging Technique: MR; Procedure: Diagnostic procedure; Special Focus: Neoplasia;
     
     
  • Figure 2
    Post contrast T1 -weighted MR images
     

    T1 w fat sat axial post contrast image shows moderate homogenous enhancement within the intraconal lesion of left orbit.

     
    Area of Interest: Neuroradiology peripheral nerve; Imaging Technique: MR; Procedure: Contrast agent-intravenous; Special Focus: Neoplasia;

    T1w sagittal fat sat post contrast image shows homogenous enhancement within the lesion.

     
    Area of Interest: Neuroradiology peripheral nerve; Imaging Technique: MR; Procedure: Contrast agent-intravenous; Special Focus: Neoplasia;
     
     
  • Figure 3
    Diffusion weighted MR images with corresponding ADC image
     

    Diffusion weighted axial image shows iso to hyperintensity lesion in intraconal space of left orbit.

     
    Area of Interest: Neuroradiology peripheral nerve; Imaging Technique: MR-Diffusion/Perfusion; Procedure: Diagnostic procedure; Special Focus: Neoplasia;

    ADC map showing area of diffusion restriction suggestive of compact cellular lesion.

     
    Area of Interest: Neuroradiology peripheral nerve; Imaging Technique: MR-Diffusion/Perfusion; Procedure: Diagnostic procedure; Special Focus: Neoplasia;
     
     
  • Figure 4
    Histopathological slides
     

    Microscopic H&E stained section shows sheets of mildly pleomorphic oval to spindled cells having fusiform nuclei and eosinophilic cytoplasm (Antoni A areas).

     
    Area of Interest: Neuroradiology peripheral nerve; Imaging Technique: Percutaneous; Procedure: Biopsy; Special Focus: Neoplasia;

    Microscopic image shows the arrangement of atypical cells in palisades with characteristic Verocay bodies.

     
    Area of Interest: Neuroradiology peripheral nerve; Imaging Technique: Percutaneous; Procedure: Biopsy; Special Focus: Neoplasia;

    Immunohistochemistry section for S-100 shows diffuse membranous and cytoplasmic positivity in spindle cells.

     
    Area of Interest: Neuroradiology peripheral nerve; Imaging Technique: Percutaneous; Procedure: Biopsy; Special Focus: Neoplasia;
     
     
T1 –weighted sagittal image shows elongated hypointense lesion in orbit.
 
T2 w coronal image shows relatively well -circumscribed hyperintensity lesion in the superomedial quadrant of intraconal space of left orbit with inseparable fat plane with optic nerve.
 
Axial FLAIR image shows well-defined iso to hypointensity lesion in the intraconal space of left orbit.
 
T1 w fat sat axial post contrast image shows moderate homogenous enhancement within the intraconal lesion of left orbit.
 
T1w sagittal fat sat post contrast image shows homogenous enhancement within the lesion.
 
Diffusion weighted axial image shows iso to hyperintensity lesion in intraconal space of left orbit.
 
ADC map showing area of diffusion restriction suggestive of compact cellular lesion.
 
Microscopic H&E stained section shows sheets of mildly pleomorphic oval to spindled cells having fusiform nuclei and eosinophilic cytoplasm (Antoni A areas).
 
Microscopic image shows the arrangement of atypical cells in palisades with characteristic Verocay bodies.
 
Immunohistochemistry section for S-100 shows diffuse membranous and cytoplasmic positivity in spindle cells.
 
 
 
Home Search Sections Teaching Cases History FAQ Case Archives Contact Login Disclaimer Imprint Switch to MOBILE version
View desktop version