EURORAD ESR

Case 14645

Neurofibromatosis mimicking perineural invasion in prostate adenocarcinoma

Author(s)
Pallavi A Patil, May M Kassem, Ali Amin

The Miriam Hospital,
Brown University;
164 Summit Ave.
02906 Providence;
Email:almin33@yahoo.com
 
Patient
male, 56 year(s)
 
 
  • Figure 1
    MRI findings of prostate adenocarcinoma in NF1
     

    (Axial T2 non-fat-saturated image) Decreased T2 signal at the right aspect correlating to PCa (black arrow). The circumscribed homogeneously T2 hyperintense mass (white arrow) correlates with neurofibroma.

     
    Area of Interest: Genital / Reproductive system male; Imaging Technique: MR; Procedure: Staging; Special Focus: Neoplasia;

    (ADC map) Area of diffusion restriction at the right apex correlates to PCa (black arrow). The circumscribed mass without diffusion restriction correlates with neurofibroma (white arrow).

     
    Area of Interest: Genital / Reproductive system male; Imaging Technique: MR; Procedure: Staging; Special Focus: Neoplasia;

    (post-gadolinium fat-saturated T1 axial) Enhancement along the left sciatic notch, initially interpreted as perineural spread (white arrow). Biopsy revealed a plexiform neurofibroma.

     
    Area of Interest: Genital / Reproductive system male; Imaging Technique: MR; Procedure: Staging; Special Focus: Neoplasia;

    Neurofibroma causing mass-effect on the prostate in the right posterior apical segment.(H&E, 10X)

     
    Area of Interest: Genital / Reproductive system male; Imaging Technique: MR; Procedure: Staging; Special Focus: Neoplasia;
     
     
(Axial T2 non-fat-saturated image) Decreased T2 signal at the right aspect correlating to PCa (black arrow). The circumscribed homogeneously T2 hyperintense mass (white arrow) correlates with neurofibroma.
 
(ADC map) Area of diffusion restriction at the right apex correlates to PCa (black arrow). The circumscribed mass without diffusion restriction correlates with neurofibroma (white arrow).
 
(post-gadolinium fat-saturated T1 axial) Enhancement along the left sciatic notch, initially interpreted as perineural spread (white arrow). Biopsy revealed a plexiform neurofibroma.
 
Neurofibroma causing mass-effect on the prostate in the right posterior apical segment.(H&E, 10X)
 
 
 
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