EURORAD ESR

Case 14530

Early MR Imaging features of Wilson disease

Author(s)
Dr. Ashim Kumar Lahiri, Dr. Balraj Dhesi

Worcestershire Royal Hospital;
Charles Hastings
Way WR5 1DD Worcester;
Email:ashim_lahiri@hotmail.com
 
Patient
male, 21 year(s)
 
 
  • Figure 1
    T2-weighted axial: bilateral symmetrical hyperintense caudate and lentiform nuclei

    T2-weighted axial images demonstrate bilateral symmetrical dominant hyperintensity of lentiform and caudate nuclei. Note of minimal signal changes in thalamus.

     
    Area of Interest: Neuroradiology brain; Imaging Technique: MR; Procedure: Imaging sequences; Special Focus: Metabolic disorders;
     
     
  • Figure 2
    T2-weighted axial images

    T2-weighted axial images demonstrate bilateral symmetrical dominant hyperintensity of basal ganglia, mixed with small low signal foci.

     
    Area of Interest: Neuroradiology brain; Imaging Technique: MR; Procedure: Imaging sequences; Special Focus: Metabolic disorders;
     
     
  • Figure 3
    Axial T1-weighted images

    Axial T1-weighted images show symmetrical reduced signal in basal ganglia.

     
    Area of Interest: Neuroradiology brain; Imaging Technique: MR; Procedure: Imaging sequences; Special Focus: Metabolic disorders;
     
     
  • Figure 4
    Axial T2* GRE images

    Axial T2* GRE images demonstrate susceptibility changes with focal hypointensities in putamen.

     
    Area of Interest: Neuroradiology brain; Imaging Technique: MR; Procedure: Imaging sequences; Special Focus: Metabolic disorders;
     
     
  • Figure 5
    T2-fluid attenuated inversion recovery (Flair) coronal images

    T2-fluid attenuated inversion recovery (Flair) coronal images reveal central reduced signal with peripheral hypointense rim, suggesting oedema/fluid contents.

     
    Area of Interest: Neuroradiology brain; Imaging Technique: MR; Procedure: Imaging sequences; Special Focus: Metabolic disorders;
     
     
T2-weighted axial images demonstrate bilateral symmetrical dominant hyperintensity of lentiform and caudate nuclei. Note of minimal signal changes in thalamus.
 
T2-weighted axial images demonstrate bilateral symmetrical dominant hyperintensity of basal ganglia, mixed with small low signal foci.
 
Axial T1-weighted images show symmetrical reduced signal in basal ganglia.
 
Axial T2* GRE images demonstrate susceptibility changes with focal hypointensities in putamen.
 
T2-fluid attenuated inversion recovery (Flair) coronal images reveal central reduced signal with peripheral hypointense rim, suggesting oedema/fluid contents.
 
 
 
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