EURORAD ESR

Case 10107

Bilateral retinoblastoma in a 8-month-old girl --- MR imaging features

Author(s)
Jacqueline CM Sitt1, Janice WL Yu1, KM Auyeung2, MK Shing3, Gladys Lo2, Winnie CW Chu1

(1) Prince of Wales Hospital
The Chinese University of Hong Kong
Diagnostic Imaging & Interventional Radiology Department
Hong Kong

(2) Hong Kong Sanitorium Hospital
Department of Diagnostic & Interventional Radiology
Hong Kong

(3) Prince of Wales Hospital
Department of Paediatrics & Adolescent Medicine
Hong Kong
 
Patient
female, 8 month(s)
 
 
  • Figure 1
    T1W Axial MR image of the orbits

    T1 hyperintense (compared with vitreous) lobulated intraocular masses are noted (arrows), suggestive of bilateral retinoblastoma with endophytic protrusion.

     
    Area of Interest: Eyes; Head and neck; Imaging Technique: MR; Procedure: Contrast agent-intravenous; Special Focus: Neoplasia;
     
     
  • Figure 2
    Fat suppressed T2W axial MR image of the orbits

    The T2 hypointensity of the retinoblastoma helps to differentiate it from other common differential diagnoses of leukocoria (most are T2 hyperintense). Intralesional signal voids (arrow) suggest presence of...

     
    Area of Interest: Eyes; Imaging Technique: MR; Procedure: Diagnostic procedure; Imaging sequences; Special Focus: Neoplasia;
     
     
  • Figure 3
    Fat-suppressed T1W Post-contrast axial MR image of the orbits

    The retinoblastoma shows strong heterogeneous contrast enhancement in post-Gadolinium T1W images. No anterior chamber enhancement, optic nerve enhancement or optic nerve extension is evident in this patient.

     
    Area of Interest: Eyes; Imaging Technique: MR; Procedure: Contrast agent-intravenous; Special Focus: Neoplasia;
     
     
T1 hyperintense (compared with vitreous) lobulated intraocular masses are noted (arrows), suggestive of bilateral retinoblastoma with endophytic protrusion.
 
The T2 hypointensity of the retinoblastoma helps to differentiate it from other common differential diagnoses of leukocoria (most are T2 hyperintense). Intralesional signal voids (arrow) suggest presence of calcifications.
 
The retinoblastoma shows strong heterogeneous contrast enhancement in post-Gadolinium T1W images. No anterior chamber enhancement, optic nerve enhancement or optic nerve extension is evident in this patient.
 
 
 
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